Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
ACROBiosystems Human Semaphorin 3A, Fc Tag (SEA-H5259) is expressed from human 293 cells (HEK293). It contains AA Lys 26 - Val 771 (Accession # Q14563-1 (R551A, R555A, R730A, K731A, R733A, R734A, R757A, R760A)).
Supplier: ACROBiosystems SEAH5259100UG
Semaphorin-3A (SEMA3A) is also known as Semaphorin III, which belongs to the semaphorin family. SEMA3A contains 1 Ig-like C2-type (immunoglobulin-like) domain, one PSI domain amd one sema domain. Semaphorin-3A is a secreted proteins, or chemorepulser, secreted by surrounding tissues to guide migrating cells and axons in the developing nervous system of an organism which is critical for the precise formation of neurons and vasculature. SEMA3A can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. In both cases, the protein is vital for normal neuronal pattern development. Increased expression of SEMA3A is associated with schizophrenia and is seen in a variety of human tumor cell lines. Also, aberrant release of this protein is associated with the progression of Alzheimer's disease.
This item is not returnable.
View return policy
Product Content Correction
The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction