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Invitrogen™ Human Semaphorin 4G ELISA Kit

Catalog No. EH406RBX5
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ELISA

Human Semaphorin 4G quantitates human Semaphorin 4G in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Semaphorin 4G.

The SEMA4G gene encodes semaphorin 4G, a member of the semaphorin protein family known for their roles in cellular guidance, signaling, and development. Semaphorin 4G is involved in axonal guidance, where it influences the direction and growth of neurons by interacting with receptor complexes such as plexins. This interaction is critical in neural development, contributing to the proper formation of neural circuits by ensuring that neurons connect accurately and functionally. Beyond its role in the nervous system, SEMA4G also participates in immune responses, where it modulates the activity and migration of immune cells, influencing processes like inflammation and immune surveillance. This protein's modulation of cell-to-cell communication and migration extends to its implications in cancer, where altered semaphorin signaling can impact tumor progression and metastasis through changes in cell adhesion and migration properties. Research into SEMA4G continues to investigate its precise mechanisms and interactions, providing insights into therapeutic opportunities in neural disorders and cancer.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q9NTN9
Assay Range 0.085-20 ng/mL
Assay Sensitivity 0.085 ng/mL
Conjugate HRP
Immunoassay Kit Format Sandwich ELISA Kit
Product Type ELISA
Sample Type Plasma, Serum, Supernatant
Target Species Human
For Use With (Equipment) Absorbance Microplate Reader
Gene Alias AI507908; AW554132; KIAA1619; KIAA1619FLJ20590; MGC102867; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G; Sema4g; semaphorin 4G; semaphorin-4GAI507908; AW554132; KIAA1619; KIAA1619FLJ20590; MGC102867; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G; Sema4g; semaphorin 4G; semaphorin-4G;
Gene ID (Entrez) 57715
Gene Symbol SEMA4G
Interassay CV <12%
Intraassay CV <10%
Kit Contents Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
Label or Dye Biotin
Quantity 5 x 96 Tests
Regulatory Status RUO
Sample Volume Plasma 50 μL, Serum 50 μL, Supernatant 50 μL
Shipping Condition Wet or Dry Ice
Storage Requirements Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C
Target SEMA4G
Test Time 1 hr 20 min
Total Assay Time 4 hr 45 min
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WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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