Invitrogen™ Human Semaphorin 6B ELISA Kit

Catalog No.	Quantity
EH408RBX10	10 x 96 Tests

Catalog No. EH408RBX10 Supplier Invitrogen™ Supplier No. EH408RBX10

Description

ELISA

Human Semaphorin 6B quantitates human Semaphorin 6B in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Semaphorin 6B.

The SEMA6B gene encodes semaphorin 6B, which belongs to the semaphorin family of proteins known for their roles in guiding axonal development and modulating cellular signaling pathways. Semaphorin 6B primarily functions in the nervous system where it influences axonal guidance, neuronal development, and synapse formation through interactions with neuropilin and plexin receptor complexes. These interactions are crucial during neural development, ensuring proper neuronal wiring and the establishment of functional neural circuits. In addition to its key role in neural connectivity, SEMA6B is increasingly recognized for its involvement in immune responses, where it can modulate the activity and migration of immune cells. In cancer biology, altered expression of SEMA6B has been implicated in tumor progression, affecting tumor cell adhesion and migration, thereby influencing metastasis. Research continues to explore the specific mechanisms of SEMA6B's action and how it can be targeted for therapeutic interventions in neural and cancer-related diseases.

Specifications

• Accession Number: Q9H3T3
• Assay Range: 0.6-150 ng/mL
• Assay Sensitivity: 0.6 ng/mL
• Conjugate: HRP
• Immunoassay Kit Format: Sandwich ELISA Kit
• Product Type: ELISA
• Sample Type: Plasma, Serum, Supernatant
• Target Species: Human
• For Use With (Equipment): Absorbance Microplate Reader
• Gene Alias: Sema; sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B; sema N; Sema VIB; sema Z; SEMA6B; SEMAN; semaphorin 6B; semaphorin VIB; semaphorin Z; semaphorin-6B; semaphorin-6Ba; semaphorin-N; Semaphorin-Z; SEMA-VIB; semaZ; SEM-SEMA-Y; UNQ1907/PRO4353; VIbSema; sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B; sema N; Sema VIB; sema Z; SEMA6B; SEMAN; semaphorin 6B; semaphorin VIB; semaphorin Z; semaphorin-6B; semaphorin-6Ba; semaphorin-N; Semaphorin-Z; SEMA-VIB; semaZ; SEM-SEMA-Y; UNQ1907/PRO4353; VIb;
• Gene ID (Entrez): 10501
• Gene Symbol: SEMA6B
• Interassay CV: <12%
• Intraassay CV: <10%
• Kit Contents: Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
• Label or Dye: Biotin
• Quantity: 10 x 96 Tests
• Regulatory Status: RUO
• Sample Volume: Plasma 50 μL, Serum 50 μL, Supernatant 50 μL
• Shipping Condition: Wet or Dry Ice
• Storage Requirements: Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C
• Target: SEMA6B
• Test Time: 1 hr 20 min
• Total Assay Time: 4 hr 45 min