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Invitrogen™ Human Semaphorin 6D ELISA Kit

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Quantity:
5 x 96 Tests
96 Tests
Description
Human Semaphorin 6D quantitates human Semaphorin 6D in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Semaphorin 6D.
Semaphorins are a large family, including both secreted and membrane associated proteins, many of which have been implicated as inhibitors or chemorepellents in axon pathfinding, fasciculation and branching, and target selection. All semaphorins possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Additional sequence motifs C-terminal to the semaphoring domain allow classification into distinct subfamilies. Results demonstrate that transmembrane semaphorins, like the secreted ones, can act as repulsive axon guidance cues. SEMA6D is a class 6 vertebrate transmembrane semaphorin that demonstrates alternative splicing. Six transcript variants have been identified and expression of the distinct encoded isoforms is thought to be regulated in a tissue- and development-dependent manner.

Specifications
Specifications
Accession Number | 1110067B02Rik; AA409156; D330011G23; FLJ11598; KIAA1479; KIAA1479FLJ11598; mKIAA1479; sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6 D; Sema6d; semaphorin 6 D; semaphorin-6 D |
Assay Range | 1.64 to 400 ng/mL |
Assay Sensitivity | 1.64 ng/mL |
Conjugate | HRP |
Product Type | ELISA |
Sample Type | Plasma, Serum, Supernatant |
For Use With (Equipment) | Colorimetric Microplate Reader |
Gene ID (Entrez) | 80031 |
Gene Symbol | SEMA6D |
Interassay CV | <12% |
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Safety and Handling
WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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