Invitrogen™ Human SHBG ELISA Kit

Description

ELISA

Human SHBG quantitates human SHBG in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human SHBG.

SHBG is a steroid binding protein that was first described as a plasma protein secreted by the liver and is thought to participate in the regulation of steroid responses. SHBG transports androgens and estrogens in the blood, binding each steroid molecule as a dimer formed from identical or nearly identical monomers. Low plasma SHBG levels are associated with obesity, abdominal adiposity, metabolic syndrome, and predict the development of type 2 diabetes. Polymorphisms in this gene have been associated with polycystic ovary syndrome and type 2 diabetes mellitus.

Specifications

• Accession Number: ABP; Abpa; androgen binding protein; SBP; sex hormone binding globulin; Sex hormone binding globulin or androgen-binding protein (other gene product from ABP gene); Sex hormone-binding globulin; Sex steroid-binding protein; Shbg; TeBG; Testis-specific androgen-binding protein; testosterone-binding beta-globulin; testosterone-estradiol-binding globulin; Testosterone-estrogen-binding globulin
• Assay Range: 1.2 to 300 pmoL/L
• Assay Sensitivity: 0.0012 pmol/mL
• Conjugate: HRP
• Product Type: ELISA
• Sample Type: Plasma, Serum, Supernatant
• For Use With (Equipment): Colorimetric Microplate Reader
• Gene ID (Entrez): 6462
• Gene Symbol: SHBG
• Interassay CV: <12%
• Intraassay CV: <10
• Kit Contents: Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
• Label or Dye: HRP
• Quantity: 5 x 96 Tests
• Regulatory Status: RUO
• Sample Volume: Plasma 50 μL, Serum 50 μL, Supernatant 50 μL
• Storage Requirements: 2°C to 8°C
• Target: SHBG
• Test Time: 1 hrs 20 mins
• Total Assay Time: 4 hrs 45 mins

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov