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ACROBiosystems Human Siglec-2 Protein, Fc Tag, Low Endotoxin, 1 mg

Catalog No. 502107292
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Human Siglec-2 (CD22) is a member of the immunoglobulin superfamily and the SIGLEC family. This protein is expressed in HEK293 cells and carries a human IgG1 Fc tag at the C-terminus, containing amino acids Asp 20 to Arg 687. It functions as an inhibitory receptor, mediating B-cell interactions and signal transduction through the recruitment of cytoplasmic phosphatases. This low endotoxin protein is verified by MALS.

  • Purity: ≥95% by SDS-PAGE and SEC-MALS.
  • Calculated MW: 101.6 kDa, migrating as 125-150 kDa due to glycosylation.
  • Endotoxin: <0.01 EU per μg by LAL/rFC method.
  • Formulation: Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH 7.5 with trehalose.
  • Recommended storage: -20°C to -70°C for 12 months in lyophilized state.

Catalog No. 50-210-7292 Supplier ACROBiosystems Supplier No. CD2H52531MG
May include imposed supplier surcharges.
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Human Siglec-2 (CD22) is a member of the immunoglobulin superfamily and the SIGLEC family. This protein is expressed in HEK293 cells and carries a human IgG1 Fc tag at the C-terminus, containing amino acids Asp 20 to Arg 687. It functions as an inhibitory receptor, mediating B-cell interactions and signal transduction through the recruitment of cytoplasmic phosphatases. This low endotoxin protein is verified by MALS.

  • Purity: ≥95% by SDS-PAGE and SEC-MALS.
  • Calculated MW: 101.6 kDa, migrating as 125-150 kDa due to glycosylation.
  • Endotoxin: <0.01 EU per μg by LAL/rFC method.
  • Formulation: Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH 7.5 with trehalose.
  • Recommended storage: -20°C to -70°C for 12 months in lyophilized state.

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