Invitrogen™ L-Selectin (CD62L) (Soluble) Human ELISA Kit
For the quantitative detection of human sL-selectin.
Manufacturer: Invitrogen™ BMS206TEN
DescriptionCD62L (L-selectin) is an adhesion glycoprotein with a molecular weight range of 74-95 kDa that is constitutively expressed on the cell surface of leukocytes, and mediates their homing to inflammatory sites and peripheral lymph nodes by enabling rolling along the venular wall. CD62L is also involved in activation-induced neutrophil aggregation. Activation-dependent CD62L shedding, however, counteracts neutrophil rolling. CD62L has also signaling roles including enhance of chemokine receptor expression. Similar to CD62P, the major ligand of CD62L is PSGL-1 (P-selectin glycoprotein ligand-1). Single-nucleotide polymorphisms in the CD26L gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for CD26L.
|2°C to 8°C|
|2 hr. 10 min.|
|Lymphocyte adhesion molecule 1, CD62L, Leu-8|
|Colorimetric Microplate Reader|
|Pre-coated 96 well plate, Standard, Sample Diluent, Assay Buffer concentrate, HRP-conjugated Detection Antibody, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers|
|Plasma, 10 μL|Serum, 10 μL|Supernatant, 10 μL|
|1 hr. 20 min.|
|10 x 96 Tests|
|Plasma, Serum, Supernatant|
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