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Invitrogen™ Human SLITRK1 Synthetic Peptide

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PEP0590 50 μg
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Catalog No. PEP0590 Supplier Invitrogen™ Supplier No. PEP0590
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Description

Synthetic Peptide

This peptide corresponds to 18 amino acids near the center of human Slitrk1. PEP-0590 can be used as a blocking peptide with polyclonal antibody PA5-20470.

SLIT and NTRK-like family 1 (Slitrk1) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the family. For example, Slitrk1 is expressed primarily in mature neurons. Overexpression of Slitrk1 in transfected neuronal cells induced unipolar neurites, while expression of the other Slitrk proteins inhibited neurite outgrowth, suggesting that these proteins are involved in the control of neurite outgrowth. While Slitrk1 variants have been suggested associated with Tourette's Syndrome, it is thought to play only a minor role if at all.
TRUSTED_SUSTAINABILITY

Specifications

Gene ID (Entrez) 114798
Species Human
Purification Method purified
Accession Number Q96PX8
Common Name SLITRK1
Concentration 200 μg/mL
Content And Storage -20°C
Description Synthetic Peptide
Format Liquid
Formulation PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
For Use With (Application) Blocking Assay, Control
Gene Alias 3200001I04Rik; KIAA1910; Leucine-rich repeat-containing protein 12; LRRC12; RP11-395N17.1; SLIT and NTRK like family member 1; SLIT and NTRK-like family, member 1; SLIT and NTRK-like protein 1; slit and trk like gene 1; SLITRK1; Sltk1; TTM; UNQ233/PRO266
Gene Symbol SLITRK1
Lyophilized No
Preservative Sodium azide
Product Type Peptide
Quantity 50 μg
Regulatory Status RUO
Storage Buffer PBS
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