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Invitrogen™ Human SMARCAL1 (aa 140-280) Control Fragment Recombinant Protein

Catalog No. RP91637
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RP91637 100 μL
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Catalog No. RP91637 Supplier Invitrogen™ Supplier No. RP91637
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Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (40%), Rat (40%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-54181. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

PRKCQ is a calcium-independent, novel isoform that is important in transducing signals in T lymphocytes. Interaction of a T lymphocyte with an antigen-presenting cell results in clustering of the T cell antigen receptor (TCR) and the recruitment of a large signaling complex to the site of cell-cell contact. PRKCQ is essential for TCR-mediated activation. PKC theta plays a role in pathways that link the TCR signaling complex to the activation of NF-kappa B in mature T lymphocytes.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q9NZC9
Concentration ≥5.0 mg/mL
For Use With (Application) Neutralization, Control
Formulation PBS, 1M urea with no preservative; pH 7.4
Gene ID (Entrez) 50485
Name Human SMARCAL1 (aa 140-280) Control Fragment
pH Range 7.4
Purification Method Purified
Quantity 100 μL
Storage Requirements -20°C, Avoid Freeze/Thaw Cycles
Regulatory Status RUO
Gene Alias 6030401P21Rik; AI851716; ATP-driven annealing helicase; DNA-dependent ATPase A; HARP; HepA-related protein; HHARP; Mharp; SMARCAL1; SMARCA-like protein 1; Sucrose nonfermenting protein 2-like 1; Swi/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1
Common Name SMARCAL1
Gene Symbol SMARCAL1
Product Type Protein
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence SYELGQGHAQASPEIRFTPFANPTHKPLAKPKSSQETPAHSSGQPPRDAKLEAKTAKASPSGQNISYIHSSSESVTPRTEGRLQQKSGSSVQKGVNSQKGKCVRNGDRFQVLIGYNAELIAVFKTLPSKNYDPDTKTWNFS
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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