Invitrogen™ Human SMPD1 ELISA Kit

Catalog No.	Quantity
EH431RBX5	5 x 96 Tests
EH431RB	96 Tests

Catalog No. EH431RBX5 Supplier Invitrogen™ Supplier No. EH431RBX5

Description

ELISA

Human SMPD1 quantitates human SMPD1 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human SMPD1.

The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB). Three transcript variants encoding two different isoforms have been found for this gene.

Specifications

• Accession Number: P17405
• Assay Range: 1.22-300 ng/mL
• Assay Sensitivity: 1.22 ng/mL
• Conjugate: HRP
• Immunoassay Kit Format: Sandwich ELISA Kit
• Product Type: ELISA
• Sample Type: Plasma, Serum, Supernatant
• Target Species: Human
• For Use With (Equipment): Absorbance Microplate Reader
• Gene Alias: Acid sphingomyelinase; ASM; aSMase; A-SMase; NPD; Smpd1; Sphingomyelin phosphodiesterase; sphingomyelin phosphodiesterase 1; sphingomyelin phosphodiesterase 1, acid lysosomal; Zn-SMaseAcid sphingomyelinase; ASM; aSMase; A-SMase; NPD; Smpd1; Sphingomyelin phosphodiesterase; sphingomyelin phosphodiesterase 1; sphingomyelin phosphodiesterase 1, acid lysosomal; Zn-SMase;
• Gene ID (Entrez): 6609
• Gene Symbol: Smpd1
• Interassay CV: <12%
• Intraassay CV: <10%
• Kit Contents: Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
• Label or Dye: Biotin
• Quantity: 5 x 96 Tests
• Regulatory Status: RUO
• Sample Volume: Plasma 50 μL, Serum 50 μL, Supernatant 50 μL
• Shipping Condition: Wet or Dry Ice
• Storage Requirements: Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C
• Target: ASM
• Test Time: 1 hr 20 min
• Total Assay Time: 4 hr 45 min

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov