Invitrogen™ Human SMU1 (aa 115-200) Control Fragment Recombinant Protein

Catalog No.	Quantity
RP92933	100 μL

Catalog No. RP92933 Supplier Invitrogen™ Supplier No. RP92933

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-53962. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

SMU1 (suppressor of Mec8 and Unc-52 homolog), also known as BWD (brain-enriched WD), is a member of the WD-repeat SMU1 family and contains one CTLH domain, one LisH domain and six WD-repeats. SMU1 is a homolog of the C. elegans protein Smu1, a ubiquitously expressed nuclear protein that is believed to play a role in alternative splicing events of Unc-52. In mammals, SMU1 is a component of the spliceosome and appears to exhibit a conserved function, affecting the splicing of the mammalian Unc-52 homolog, namely Perlecan. Mutations in the gene encoding SMU1 may affect the function of the spliceosome.

Specifications

• Accession Number: Q2TAY7
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Neutralization, Control
• Formulation: PBS, 1M urea with no preservative; pH 7.4
• Gene ID (Entrez): 55234
• Name: Human SMU1 (aa 115-200) Control Fragment
• pH Range: 7.4
• Purification Method: Purified
• Quantity: 100 μL
• Storage Requirements: -20°C, Avoid Freeze/Thaw Cycles
• Regulatory Status: RUO
• Gene Alias: 2600001O03Rik; 2610203K23Rik; AB044414; AI845086; AW556129; Brain-enriched WD repeat-containing protein; brain-enriched WD-repeat protein; BWD; DNA replication regulator and spliceosomal factor; fSAP57; functional spliceosome-associated protein 57; homolog of C. elegans smu-1; SMU1; SMU-1; smu-1 suppressor of mec-8 and unc-52 homolog; smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans); smu-1 suppressor of mec-8 and unc-52 protein homolog; suppressor of Mec and Unc defects 1 homolog; WD40 repeat-containing protein SMU1; WD40 repeat-containing protein SMU1, N-terminally processed
• Common Name: SMU1
• Gene Symbol: Smu1
• Product Type: Protein
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-ABP-tag
• Sequence: IHLENLLARSYFDPREAYPDGSSKEKRRAAIAQALAGEVSVVPPSRLMALLGQALKWQQHQGLLPPGMTIDLFRGKAAVKDVEEEK
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Purity or Quality Grade: >80% by SDS-PAGE and Coomassie blue staining