Invitrogen™ Human SPANXC (aa 33-58) Control Fragment Recombinant Protein

Catalog No.	Quantity
RP99048	100 μL

Catalog No. RP99048 Supplier Invitrogen™ Supplier No. RP99048

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (42%), Rat (42%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-83819. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family, which is located in a gene cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene encodes a protein that localizes to the nucleus and is expressed in highly metastatic cell lines, making the protein a potential diagnostic and prognostic marker. The protein belongs to a family of cancer/testis antigens and represents a potential target for cancer immunotherapy.

Specifications

• Accession Number: Q9NY87
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Neutralization, Control
• Formulation: PBS, 1M urea with no preservative; pH 7.4
• Gene ID (Entrez): 64663
• Name: Human SPANXC (aa 33-58) Control Fragment
• pH Range: 7.4
• Purification Method: Purified
• Quantity: 100 μL
• Storage Requirements: -20°C, Avoid Freeze/Thaw Cycles
• Regulatory Status: RUO
• Gene Alias: C; cancer/testis antigen 11.3; cancer/testis antigen family 11, member 3; cancer/testis-associated protein CTp11; cancer/testis-associated protein of 11 kD; cancer-testis-associated protein CTp11; CT11.3; CTp11; nuclear-associated protein SPAN-Xc; SPANX family member C; SPANX family, member C; SPANXC; SPANX-C; SPAN-Xc protein; Sperm protein associated with the nucleus on the X chromosome C; sperm protein associated with the nucleus, X chromosome, family member C
• Common Name: SPANXC
• Gene Symbol: SPANXC
• Product Type: Protein
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-ABP-tag
• Sequence: SDPQPAPKKLKTSESSTILVVRYRRN
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Purity or Quality Grade: >80% by SDS-PAGE and Coomassie blue staining