Invitrogen™ Human TEM8 Synthetic Peptide

Catalog No.	Quantity
PEP0136	50 μg

Catalog No. PEP0136 Supplier Invitrogen™ Supplier No. PEP0136

Description

Synthetic Peptide

This peptide corresponds to 13 amino acids near the C-terminus of human TEM8. PEP-0136 can be used as a blocking peptide with polyclonal antibody PA5-20017.

This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described.

Specifications

• Gene ID (Entrez): 84168
• Species: Human
• Purification Method: purified
• Accession Number: Q9H6X2
• Common Name: TEM8
• Concentration: 200 μg/mL
• Content And Storage: -20°C
• Description: Synthetic Peptide
• Format: Liquid
• Formulation: PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
• For Use With (Application): Blocking Assay, Control
• Gene Alias: 2310008J16Rik; 2810405N18Rik; anthrax toxin receptor; anthrax toxin receptor 1; Antrx1; ANTXR1; ATR; FLJ10601; FLJ11298; FLJ21776; GAPO; TEM8; Tem-8; tumor endothelial marker 8
• Gene Symbol: ANTXR1
• Lyophilized: No
• Preservative: Sodium azide
• Product Type: Peptide
• Quantity: 50 μg
• Regulatory Status: RUO
• Storage Buffer: PBS

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov