Invitrogen™ Human Thimet Oligopeptidase/THOP1 ELISA Kit

Catalog No.	Quantity
EH450RBX10	10 x 96 Tests

Catalog No. EH450RBX10 Supplier Invitrogen™ Supplier No. EH450RBX10

Description

ELISA

Human Thimet Oligopeptidase/THOP1 quantitates human Thimet Oligopeptidase/THOP1 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Thimet Oligopeptidase/THOP1.

A steady-state level of amyloid beta-peptide (Abeta) represents a balance between its biosynthesis from the amyloid precursor protein (APP) through the action of the beta and gamma-secretases and its catabolism by a variety of proteolytic enzymes. Thimet Oligopeptidase (THOP1) has been shown to promote A-beta degradation. It has also been shown to play a role in antigen presentation, metabolism of neuropeptides under 20 amino acids, and cytoplasmic peptide degradation.

Specifications

• Accession Number: P52888
• Assay Range: 0.35-200 ng/mL
• Assay Sensitivity: 0.9 ng/mL
• Conjugate: HRP
• Immunoassay Kit Format: Sandwich ELISA Kit
• Product Type: ELISA
• Sample Type: Plasma, Serum, Supernatant
• Target Species: Human
• For Use With (Equipment): Absorbance Microplate Reader
• Gene Alias: AI131655; AI327041; EC 3.4.24; EC 3.4.24.15; endo-oligopeptidase A; Endopeptidase 24.15; EP24.15; MEPD_HUMAN; metalloendopeptidase; MP78; PZ-peptidase; soluble metallo-endopeptidase; Thimet oligopeptidase; thimet oligopeptidase 1; Thop1; TOPAI131655; AI327041; EC 3.4.24; EC 3.4.24.15; endo-oligopeptidase A; Endopeptidase 24.15; EP24.15; MEPD_HUMAN; metalloendopeptidase; MP78; PZ-peptidase; soluble metallo-endopeptidase; Thimet oligopeptidase; thimet oligopeptidase 1; Thop1; TOP;
• Gene ID (Entrez): 7064
• Gene Symbol: Thop1
• Interassay CV: <12%
• Intraassay CV: <10%
• Kit Contents: Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
• Label or Dye: Biotin
• Quantity: 10 x 96 Tests
• Regulatory Status: RUO
• Sample Volume: Plasma 50 μL, Serum 50 μL, Supernatant 50 μL
• Shipping Condition: Wet or Dry Ice
• Storage Requirements: Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C
• Target: Thimet Oligopeptidase
• Test Time: 1 hr 20 min
• Total Assay Time: 4 hr 45 min