Invitrogen™ Human TNPO3 Synthetic Peptide

Catalog No.	Quantity
PEP0670	50 μg

Catalog No. PEP0670 Supplier Invitrogen™ Supplier No. PEP0670

Description

Synthetic Peptide

TNPO3 Synthetic Peptide, PEP-0670, from Invitrogen.

TNPO3 is a member of the importin beta/transportin family of nuclear import receptors and is specific for the essential splicing factors termed SR proteins, binding specifically and directly to the arginine/serine (RS)-rich domains of these proteins. Further experiments demonstrated that this interaction occurs only when these RS domains are phosphorylated. More recently, TNPO3 was identified as an HIV dependency factor (HDF) and that depletion of TNPO3 resulted in HIV inhibition after reverse transcription but before integration, suggesting that TNPO3 may be an important drug target in HIV treatment. At least three isoforms of TNPO3 are known to exist.

Specifications

• Gene ID (Entrez): 23534
• Species: Human
• Purification Method: purified
• Accession Number: Q9Y5L0
• Common Name: Human TNPO3
• Concentration: 200 μg/mL
• Content And Storage: -20°C
• Description: Synthetic Peptide
• Format: Liquid
• Formulation: PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
• For Use With (Application): Blocking Assay, Control
• Gene Symbol: TNPO3
• Lyophilized: No
• Preservative: 0.02% sodium azide
• Product Type: Peptide
• Quantity: 50 μg
• Regulatory Status: RUO - research use only
• Storage Buffer: PBS

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov