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Invitrogen™ Human TPRKB (aa 1-80) Control Fragment Recombinant Protein

Catalog No. RP96112
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RP96112 100 μL
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Catalog No. RP96112 Supplier Invitrogen™ Supplier No. RP96112
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Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (91%), Rat (91%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-83281. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

TPRKB is a component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. TPRKB acts as an allosteric effector that regulates the t6A activity of the complex. TPRKB is not required for tRNA modification.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q9Y3C4
Concentration ≥5.0 mg/mL
For Use With (Application) Neutralization, Control
Formulation PBS, 1M urea with no preservative; pH 7.4
Gene ID (Entrez) 51002
Name Human TPRKB (aa 1-80) Control Fragment
pH Range 7.4
Purification Method Purified
Quantity 100 μL
Storage Requirements -20°C, Avoid Freeze/Thaw Cycles
Regulatory Status RUO
Gene Alias 0610033G21Rik; 1810034M08Rik; CGI121; Cgi-121; DRWMS1; EKC/KEOPS complex subunit TPRKB; mDRWMS1; My019; Prpk (p53-related protein kinase)-binding protein; PRPK-binding protein; RGD1309786; Tp53rk binding protein; TP53RK-binding protein; TP53RK-binding protein; EKC/KEOPS complex subunit TPRKB; TPRKB; WBSCR18; zgc:101896
Common Name TPRKB
Gene Symbol TPRKB
Product Type Protein
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence MQLTHQLDLFPECRVTLLLFKDVKNAGDLRRKAMEGTIDGSLINPTVIVDPFQILVAANKAVHLYKLGKMKTRTLSTEII
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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