Invitrogen™ Human TRPC3 Synthetic Peptide

Catalog No.	Quantity
PEP0391	50 μg

Catalog No. PEP0391 Supplier Invitrogen™ Supplier No. PEP0391

Description

Synthetic Peptide

This peptide corresponds to 14 amino acids near the amino terminus of human TRPC3. PEP-0391 can be used as a blocking peptide with polyclonal antibody PA5-20255.

The mammalian transient receptor potential (TRP) superfamily can be divided into three major families including the 'canonical TRP' (TRPC) family. The seven members of this family share the activation through PLC-coupled receptors and have been suggested to be components of receptor-regulated cation channels in different cell types. Furthermore, the members of the TRPC3/6/7 subfamily can be activated by diacylglycerol analogs, suggesting a possible mechanism of activation of these channels by PLC-coupled receptors. TRPC3 encodes a Ca2+-permeant channel that is agonist-activated but not store-operated or directly receptor-activated. TRPC3 physically interacts with TRPC6 and TRPC7 and forms functional tetrameric channels.

Specifications

• Gene ID (Entrez): 7222
• Species: Human
• Purification Method: purified
• Accession Number: Q13507
• Common Name: TRPC3
• Concentration: 200 μg/mL
• Content And Storage: -20°C
• Description: Synthetic Peptide
• Format: Liquid
• Formulation: PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
• For Use With (Application): Blocking Assay, Control
• Gene Alias: hTrp3; hTrp-3; ion channel protein; mTrp3; Mwk; receptor-activated cation channel TRP3; SCA41; Short transient receptor potential channel 3; transient receptor potential cation channel subfamily C member 3; transient receptor potential cation channel subfamily C member 3 variant c; transient receptor potential cation channel, subfamily C, member 3; transient receptor protein 3; Trcp3; Trp3; TRP-3; TRPC3; TrpC3c; trp-related protein 3; Trrp3
• Gene Symbol: Trpc3
• Lyophilized: No
• Preservative: Sodium azide
• Product Type: Peptide
• Quantity: 50 μg
• Regulatory Status: RUO
• Storage Buffer: PBS