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Invitrogen™ Human Trypsin (aa 68-97) Control Fragment Recombinant Protein

Catalog No. RP104539
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RP104539 100 μL
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Catalog No. RP104539 Supplier Invitrogen™ Supplier No. RP104539
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Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (90%), Rat (90%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-111565. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Trypsin is a 24 kDa enzyme of the serine proteinase family. It is produced in the pancreas as an inactive precursor, trypsinogen, but the active enzyme is located in the gastrointestinal tract where it degrades proteins to large peptides. Trypsin prefers lysine and arginine residues. One of the substrates for trypsin is chymotrypsinogen which is cleaved to produce active chymotrypsin. High levels of immunoreactive trypsin in the bloodstream can indicate pancreatic malfunction and this indicator is used to screene for and diagnose Cystic Fibrosis.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P07477
Concentration ≥5.0 mg/mL
For Use With (Application) Neutralization, Control
Formulation PBS, 1M urea with no preservative; pH 7.4
Gene ID (Entrez) 5644
Name Human Trypsin (aa 68-97) Control Fragment
pH Range 7.4
Purification Method Purified
Quantity 100 μL
Storage Requirements -20°C, Avoid Freeze/Thaw Cycles
Regulatory Status RUO
Gene Alias Alpha-trypsin chain 1; Alpha-trypsin chain 2; Anionic trypsin I; anionic trypsin-1; Anionic trypsinogen; beta-trypsin; Cationic trypsinogen; digestive zymogen; MGC120175; MGC149362; nonfunctional trypsin 1; pancreatic trypsin 1; pretrypsinogen I; Protease Serine 1; protease serine 2 preproprotein; protease, serine 1; protease, serine 1 (trypsin 1); protease, serine 2; protease, serine, 1; protease, serine, 1 (trypsin 1); protease, serine, 2; protease, serine, 2 (trypsin 2); PRSS1; PRSS2; PTRYI; RATPTRYI; Serine protease 1; Serine protease 2; TCR V beta 4.1; TRP1; Try1; Try-1; TRY2; TRY4; TRY8; Trygn16; TRYP1; TRYP2; TRYP8; trypsin 1; Trypsin I; Trypsin II; trypsin-1; Trypsin-2; trypsinogen; trypsinogen 1; trypsinogen 16; trypsinogen 2; trypsinogen A
Common Name Trypsin
Gene Symbol PRSS1
Product Type Protein
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence RIQVRLGEHNIEVLEGNEQFINAAKIIRHP
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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