Invitrogen™ Human TTYH2 Synthetic Peptide

Catalog No.	Quantity
PEP1437	50 μg

Catalog No. PEP1437 Supplier Invitrogen™ Supplier No. PEP1437

Description

Synthetic Peptide

This peptide corresponds to 14 amino acid peptide near the amino terminus of human TTYH2. PEP-1437 can be used as a blocking peptide with polyclonal antibody PA5-34395.

TTYH2 is a member of the tweety family of proteins, a family of chloride anion channels containing five transmembrane regions. TTYH2 is a Ca2+-activated large conductance chloride (Cl-) channel and may play a role in kidney tumorigenesis. It is also upregulated in colon carcinoma and is thought to play a role in cell proliferation and call aggregation, suggesting that TTYH2 may play a role in regulating both proliferation and metastatic potentials of colorectal cancer. The ubiquitin-protein ligase Nedd4-2 binds to and ubiquitinates TTYH2, thereby regulating its cell surface expression and total cellular levels.

Specifications

• Gene ID (Entrez): 94015
• Species: Human
• Purification Method: purified
• Accession Number: Q9BSA4
• Common Name: TTYH2
• Concentration: 200 μg/mL
• Content And Storage: -20°C
• Description: Synthetic Peptide
• Format: Liquid
• Formulation: PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
• For Use With (Application): Blocking Assay, Control
• Gene Alias: 1110001A03Rik; C17orf29; hTTY2; mTTY2; Protein tweety homolog 2; RGD1562969; TTYH2; tweety family member 2; tweety homolog 2; tweety homolog 2 (Drosophila)
• Gene Symbol: TTYH2
• Lyophilized: No
• Preservative: Sodium azide
• Product Type: Peptide
• Quantity: 50 μg
• Regulatory Status: RUO
• Storage Buffer: PBS