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Invitrogen™ Human TWIST2 (aa 21-70) Control Fragment Recombinant Protein

Catalog No. RP107203
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RP107203 100 μL
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Catalog No. RP107203 Supplier Invitrogen™ Supplier No. RP107203
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Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-66539. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Binds to the E-box consensus sequence 5'-CANNTG-3' as a heterodimer and inhibits transcriptional activation by MYOD1, MYOG, MEF2A and MEF2C. Also represses expression of proinflammatory cytokines such as TNFA and IL1B. Involved in postnatal glycogen storage and energy metabolism. Inhibits the premature or ectopic differentiation of preosteoblast cells during osteogenesis, possibly by changing the internal signal transduction response of osteoblasts to external growth factors.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q8WVJ9
Concentration ≥5.0 mg/mL
For Use With (Application) Neutralization, Control
Formulation PBS, 1M urea with no preservative; pH 7.4
Gene ID (Entrez) 117581
Name Human TWIST2 (aa 21-70) Control Fragment
pH Range 7.4
Purification Method Purified
Quantity 100 μL
Storage Requirements -20°C, Avoid Freeze/Thaw Cycles
Regulatory Status RUO
Gene Alias AMS; BBRSAY; bHLHa39; Class A basic helix-loop-helix protein 39; dermis expressed 1; dermis-expressed protein 1; DERMO1; Dermo-1; dermo-1 protein; FFDD3; SETLSS; twist basic helix-loop-helix transcription factor 2; twist family bHLH transcription factor 2; twist homolog 2; TWIST2; twist-related bHLH protein Dermo1; twist-related protein 2
Common Name TWIST2
Gene Symbol TWIST2
Product Type Protein
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence ELERQPKRFGRKRRYSKKSSEDGSPTPGKRGKKGSPSAQSFEELQSQRIL
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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