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Invitrogen™ Human UBC3B (aa 192-214) Control Fragment Recombinant Protein

Catalog No. RP105163
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RP105163 100 μL
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Catalog No. RP105163 Supplier Invitrogen™ Supplier No. RP105163
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Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-66358. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Protein kinase CK2 is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing beta-catenin degradation.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q712K3
Concentration ≥5.0 mg/mL
For Use With (Application) Neutralization, Control
Formulation PBS, 1M urea with no preservative; pH 7.4
Gene ID (Entrez) 54926
Name Human UBC3B (aa 192-214) Control Fragment
pH Range 7.4
Purification Method Purified
Quantity 100 μL
Storage Requirements -20°C, Avoid Freeze/Thaw Cycles
Regulatory Status RUO
Gene Alias 1200003M11Rik; CDC34B; cell division cycle 34 homolog; E2 ubiquitin-conjugating enzyme R2; E2-CDC34B; LOC689226; similar to ubiquitin-conjugating enzyme E2R 2; UBC3B; Ube2r2; Ubiquitin carrier protein R2; ubiquitin conjugating enzyme E2 R2; ubiquitin conjugating enzyme E2R 2; ubiquitin-conjugating enzyme E2 R2; ubiquitin-conjugating enzyme E2-32k; ubiquitin-conjugating enzyme E2-CDC34B; ubiquitin-conjugating enzyme E2R 2; ubiquitin-conjugating enzyme UBC3B; ubiquitin-protein ligase R2
Common Name UBC3B
Gene Symbol UBE2R2
Product Type Protein
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence IKTKVPSNDNSSDLLYDDLYDDD
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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