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ILEX LIFE SCIENCES LLC Urokinase Human Purified Protein (1 mg)
Supplier: ILEX LIFE SCIENCES LLC A42641000
Urokinase Human Purified Protein is a two-chain glycoprotein containing 411 amino acids with 12 disulfide bonds. It has a 54 kDa molecular weight. SOURCE: The enzyme is purified from human urine. FORMULATION: Sterile filtered white lyophilized (freeze-dried) powder. The enzyme was lyophilized from a concentrated (1 mg/ml) solution containing phosphate buffer. PURITY: Greater than 90.0%. SPECIFIC ACTIVITY: 187,973 IU/mg (may vary slightly with each lot, please refer to the enclosed COA with your product). CONTAMINANTS: Free of Hepatitis B surface antigen, Hepatitis C antibody, HIV I and HIV II. SUMMARY: Urokinase is a serine protease that specifically cleaves the zymogen plasminogen to form the active enzyme plasmin. It is involved in numerous biological functions including fibrinolysis, embryogenesis, cell migration, tissue remodeling, ovulation, and wound healing. SYNONYMS: EC:3.4.21.73, urokinase-type plasminogen activator, UK, U-plasminogen activator, uPA.
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