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Invitrogen™ Human USP49 (aa 104-181) Control Fragment Recombinant Protein

Catalog No. RP94935
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RP94935 100 μL
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Catalog No. RP94935 Supplier Invitrogen™ Supplier No. RP94935
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Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (86%), Rat (86%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-56416. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Specifically deubiquitinates histone H2B at 'Lys-120' (H2BK120Ub). H2BK120Ub is a specific tag for epigenetic transcriptional activation and acts as a regulator of mRNA splicing. Deubiquitination is required for efficient cotranscriptional splicing of a large set of exons.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q70CQ1
Concentration ≥5.0 mg/mL
For Use With (Application) Neutralization, Control
Formulation PBS, 1M urea with no preservative; pH 7.4
Gene ID (Entrez) 25862
Name Human USP49 (aa 104-181) Control Fragment
pH Range 7.4
Purification Method Purified
Quantity 100 μL
Storage Requirements -20°C, Avoid Freeze/Thaw Cycles
Regulatory Status RUO
Gene Alias C330046L10Rik; deubiquitinating enzyme 49; Gm545; RGD1310513; ubiquitin carboxyl-terminal hydrolase 49; ubiquitin specific peptidase 49; ubiquitin specific protease 49; ubiquitin thioesterase 49; ubiquitin thiolesterase 49; ubiquitin-specific-processing protease 49; Usp49
Common Name USP49
Gene Symbol USP49
Product Type Protein
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence GQKQDTPVRRGRTLRSMASGEDVVLPQRAPQGQPQMLTALWYRRQRLLARTLRLWFEKSSRGQAKLEQRRQEEALERK
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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