Invitrogen™ Human WAC Synthetic Peptide

Catalog No.	Quantity
PEP1579	50 μg

Catalog No. PEP1579 Supplier Invitrogen™ Supplier No. PEP1579

Description

Synthetic Peptide

This peptide corresponds to 19 amino acids near the center of human WAC. PEP-1579 can be used as a blocking peptide with polyclonal antibody PA5-34536. For use as a blocking peptide in Western blot, incubate the peptide with equal volume of antibody for 30 min at 37°C.

The WW domain containing adaptor with coiled-coil protein (WAC) contains a WW domain that mediates protein-protein interactions and colocalizes with RNA splicing factor SC35. Further studies have indicated that WAC is a functional partner of the RNF20/40 complex that ubiquitinates Histone H2B, and that WAC regulates H2B ubiquitination. WAC targets RNF20/40 to associate with RNA polymerase II complex for H2B ubiquitination at active transcription sites. WAC-dependent transcription is also important for cell-cycle checkpoint activation in response to genotoxic stress.

Specifications

• Gene ID (Entrez): 51322
• Species: Human
• Purification Method: purified
• Accession Number: Q9BTA9
• Common Name: WAC
• Concentration: 200 μg/mL
• Content And Storage: -20°C
• Description: Synthetic Peptide
• Format: Liquid
• Formulation: PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
• For Use With (Application): Blocking Assay, Control
• Gene Alias: 1110067P07Rik; A230035H12Rik; AI256735; AI256776; BM-016; DESSH; Kiaa1844; PRO1741; RGD1562407; Wac; WW domain containing adaptor with coiled-coil; WW domain-containing adapter protein with coiled-coil; WW domain-containing adaptor with coiled-coil; WW domain-containing protein 4; Wwp4
• Gene Symbol: Wac
• Lyophilized: No
• Preservative: Sodium azide
• Product Type: Peptide
• Quantity: 50 μg
• Regulatory Status: RUO
• Storage Buffer: PBS