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Cayman Chemical Humn FarnsoId X Receptr Re 96
Supplier: Cayman Chemical 1574196 WELL
A fluoroquinolone antibiotic active against a variety of Gram-positive and Gram-negative bacteria in vitro including S. aureus L. monocytogenes P. aeruginosa Legionella N. gonorrhoeae and H. pylori (MIC50s 0.004-1 Ug/ml) active against clinical isolates of Bacteroides Fusobacterium Eubacterium Actinomyces Peptococcus Peptostreptococcus and Streptococcus in vitro (MIC50s 0.5-2 Ug/ml) inhibits S. aureus DNA gyrase and topoisomerase IV (IC50s 13.5 and 5.76 Ug/ml respectively) reduces mortality in mouse models of intraperitoneal E. coli P. vulgaris K. pneumoniae P. aeruginosa and S. aureus infection (ED90-100s 1-5 2.5-5 5-10 20-40 and 80 mg/kg respectively) prevents mortality in a mouse model of subcutaneous S. typhimurium infection at 10 mg/kg
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