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Cayman Chemical Humn FIbrInogen AFInIty1.2mL
Supplier: Cayman Chemical 4012721.2 ML
An ionizable cationic lipid that has been used in the generation of LNPs LNPs containing 244cis and encapsulating an mRNA reporter specifically accumulate in the lungs and induce lower Ccl2 levels than LNPs containing SM-102 in mice intravenous administration of LNPs containing 244cis and encapsulating mRNA encoding Cre recombinase increases tdTomato fluorescence in lung endothelial epithelial and immune cells as well as fibroblasts in mice expressing a floxed STOP codon to prevent tdTomato expression LNPs containing 244cis and encapsulating siRNA targeting the gene encoding Gtse1 reduce hepatic fibrosis with decreased production of Il-6 and Tnf-a and induction of ALT and AST compared with LNPs containing SM-102 in a mouse model of carbon tetrachloride-induced liver injury
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