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Cayman Chemical Humn Hepatocyte Nuclear Fact
SDP

Supplier:  Cayman Chemical 41010384 WELL

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A chalcone with enzyme inhibitory and anticancer activities inhibits collagenase and elastase in cell-free assays (IC50s 62.05 and 17.6 UM respectively) cytotoxic to HCT116 HT-29 MCF-7 A549 and Ca Ski cancer cells (IC50s 12.75 39 47.63 40.28 and 39.88 UM respectively) induces apoptosis and cell cycle arrest at the G1 phase in HCT116 cells at 20 40 and 60 UM reduces tumor volume and induces intratumoral necrosis and apoptosis in an HCT116 mouse xenograft model at 1 and 3 mg/kg

Catalog No. 50-294-2526


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