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Cayman Chemical Humn Trnsformng Growth Fac 96
SDP

Supplier:  Cayman Chemical 3025596 WELL

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An inhibitor of DYRK1A DYRK2 CLK1 and CLK3 (IC50s 0 04 0 035 0 015 and 4 5 UM respectively) an inhibitor of GSK3a/B and Pim1 (IC50s 0 41and 4 1 UM respectively) inhibits TNF-a-induced SRp75 and SRp55 phosphorylation in human microvascular endothelial cells at 0 1-10 UM modulates alternative pre-RNA splicing of a synthetic CLK1 minigene prevents amyloid-B 25-35-induced lipid peroxidation and ROS accumulation in the hippocampus in a mouse model of Alzheimers disease-like toxicity prevents amyloid-B 25-35-induced memory deficits in the same model at 0 4 1 2 and 4 Ug

Catalog No. 50-298-9158


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