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Apexbio Technology LLC (-)-Huperzine A 102518-79-6 10mM (in 1mL DMSO)
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Supplier:  Apexbio Technology LLC A19325.1

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(-)-Huperzine A (CAS 102518-79-6) known as HupA is an alkaloid compound serving as an inhibitor of acetylcholinesterase (AChE) with an IC50 value of 82 nmol/L By suppressing AChE activity HupA reduces the enzymatic breakdown of neurotransmitter acetylcholine potentially alleviating symptoms associated with Alzheimer s disease Furthermore HupA acts as a non-competitive antagonist at NMDA receptors attenuating NMDA-induced currents in rat hippocampal neurons Studies demonstrate sustained AChE inhibition lasting up to 360 minutes following systemic administration Consequently HupA has significant applications in neuropharmacological research targeting cognitive disorders and neuroprotection

Catalog No. 50-000-63681


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