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Medchemexpress LLC Hxr9 hydrochloride | 99.5% | 2754.67 | 5 MG
Supplier: Medchemexpress LLC HYP3245A5MG
HXR9 hydrochloride is a cell-permeable peptide and a competitive antagonist of HOX/PBX interaction. It antagonizes the interaction between HOX and PBX, a transcription factor that binds to HOX proteins in paralogue groups 1 to 8. It selectively decreases cell proliferation and promotes apoptosis in cells with high HOXA/PBX3 genes expression, such as MLL-rearranged leukemic cells.
- Cell-permeable peptide
- Competitive antagonist of HOX/PBX interaction
- Decreases cell proliferation in cells with high HOXA/PBX3 genes expression
- Promotes apoptosis in cells with high HOXA/PBX3 genes expression
- Blocks the interaction between PBX and HOX
- Exhibits antiproliferative activity
- Blocks tumor growth in vivo
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