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Medchemexpress LLC Hydrangenol | 480-47-7 | 1 MG
SDP

Supplier:  Medchemexpress LLC HYN40281MG

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Hydrangenol is an orally active antiphotoaging compound isolated from Hydrangea serrata leaves. It prevents wrinkle formation by reducing MMP and inflammatory cytokine expression, and by increasing moisturizing factors and antioxidant gene levels.

  • Reduces wrinkle formation, dorsal thickness, dehydration, and collagen degradation
  • Increases expression of involucrin, filaggrin, and aquaporin-3 (AQP3)
  • Promotes hyaluronic acid (HA) production
  • Decreases matrix metalloproteinase (MMP)-1/-3, cyclooxygenase-2 (COX-2), and interleukin-6 (IL-6) expression
  • Attenuates phosphorylation of MAPKs (ERK and p38)
  • Upregulates Nrf2, HO-1, NQO-1, GCLM, and GCLC expression

Catalog No. 50-004-19321


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