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Medchemexpress LLC Hydrochlorothiazide | 58-93-5 | MFCD00051765 | 99.5% | 5 G
Supplier: Medchemexpress LLC HYB02525G
Hydrochlorothiazide (HCTZ) is an orally active thiazide diuretic that inhibits the TGF-β/Smad signaling pathway and has direct vascular relaxant effects. It improves cardiac function, reduces fibrosis, and exhibits an antihypertensive effect by reducing sodium reabsorption in the kidneys and lowering peripheral vascular resistance.
- Orally active diuretic agent
- Inhibits the TGF-β/Smad signaling pathway
- Direct vascular relaxant effects by opening KCA channels
- Improves cardiac function
- Reduces fibrosis
- Antihypertensive effect
- Reduces blood volume by decreasing sodium reabsorption
- Induces natriuresis and concomitant water loss
- Increases calcium reabsorption
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