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Medchemexpress LLC Hydrocortisone cypionate | 508-99-6 | 486.64 | 5 MG
Supplier: Medchemexpress LLC HYU000895MG
Hydrocortisone cypionate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester. It is intended for research use only.
- Down-regulates GR transcript in hCMEC/D3 cells in a dose-dependent manner.
- Supplementation leads to a significant increase in TER across the hCMEC/D3 monolayer.
- Treated dendritic cells (DCs) exhibit decreased expression of MHC II molecules, costimulatory molecule CD86, and DC-specific marker CD83.
- Treated dendritic cells (DCs) show strongly reduced IL-12 secretion.
- Treated dendritic cells (DCs) inhibit IFN-γ production but induce increased release of IL-4.
- Reduces post-ischemic oxidative stress, perfusion pressure, and transudate formation.
- Inhibits post-ischemic shedding of syndecan-1, heparan sulfate, and hyaluronan.
- Inhibits histamine release from mast cells.
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