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Medchemexpress LLC Hydrocortisone cypionate | 508-99-6 | MFCD00083363 | 486.64 | 20 MG
SDP

Catalog No. 5000448558
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Hydrocortisone cypionate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester, intended for research use only. It demonstrates diverse biological activities in vitro.

  • Shows dose-dependent down-regulation of GR transcript in hCMEC/D3 cells and significantly increases TER across the hCMEC/D3 monolayer.
  • Decreases expression of MHC II molecules, costimulatory molecule CD86, and DC-specific marker CD83 in treated dendritic cells, along with strongly reduced IL-12 secretion.
  • Inhibits IFN-γ production but induces increased IL-4 release in dendritic cells.
  • Reduces postischemic oxidative stress, perfusion pressure, transudate formation.
  • Inhibits postischemic shedding of syndecan-1, heparan sulfate, and hyaluronan, as well as histamine release from mast cells.

Catalog No. 50-004-48558 Supplier Medchemexpress LLC Supplier No. HYU0008920MG
May include imposed supplier surcharges.
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Hydrocortisone cypionate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester, intended for research use only. It demonstrates diverse biological activities in vitro.

  • Shows dose-dependent down-regulation of GR transcript in hCMEC/D3 cells and significantly increases TER across the hCMEC/D3 monolayer.
  • Decreases expression of MHC II molecules, costimulatory molecule CD86, and DC-specific marker CD83 in treated dendritic cells, along with strongly reduced IL-12 secretion.
  • Inhibits IFN-γ production but induces increased IL-4 release in dendritic cells.
  • Reduces postischemic oxidative stress, perfusion pressure, transudate formation.
  • Inhibits postischemic shedding of syndecan-1, heparan sulfate, and hyaluronan, as well as histamine release from mast cells.

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