Sigma Aldrich Hydroxy-Peg6-T-Butyl Ester

Catalog No.	Quantity
90-257-8250MG	1 g

Catalog No. 90-257-8250MG Supplier Sigma Aldrich Supplier No. 902578250MG

Description

MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.

This heterobifunctional, PEGylated crosslinker features a hydroxyl group at one end and t-butyl-protected carboxylic acid at the other, which can be deprotected with acidic conditions. The hydrophillic PEG linker facilitates solubility in biological applications. Hydroxy-PEG6-t-butyl ester can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or roteolysis-targeting chimeras (PROTAC™ molecules) for targeted protein degradation.Synthesis and Molecular Recognition Studies of the HNK-1 Trisaccharide and Related Oligosaccharides. The Specificity of Monoclonal Anti-HNK-1 Antibodies as Assessed by Surface Plasmon Resonance and STD NMRMaleimide-oligo(ethylene glycol) Derivatives of Camptothecin as Albumin-Binding Prodrugs: Synthesis and Antitumor EfficacyPROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

Specifications

• CAS: 37026-88-3
• Molecular Formula: C30H48BF4P2Rh
• Linear Formula: C30H48BF4P2Rh
• Quantity: 1 g
• Synonym: tert-Butyl 1-hydroxy-3,6,9,12,15,18-hexaoxahenicosan-21-oate; HO-PEG6-CO-OtBu
• Molecular Weight (g/mol): 660.36 g/mol
• Biological Activity: Respiratory System