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AdipoGen Hydroxychloroquine sulfate
Supplier: AdipoGen AGCR13720G001
Chemical. CAS 747-36-4. Formula C18H26ClN3O . H2SO4. MW 335.9 . 98.1. Hydroxychloroquine is a synthetic less toxic derivative of chloroquine Prod. No. AG-CR1-3721, commonly used as an antimalarial drug. Hydroxychloroquine has anti-inflammatory, immunomodulating, anti-infective, antiviral, antithrombotic and metabolic effects. It has anticancer properties, related to their strong antiproliferative, antimutagenic, epigenetic and autophagy inhibiting and apoptosis inducing activities. Hydroxychloroquine is used to treat rheumatoid arthritis, systemic lupus erythematosus, antiphospholipid antibody syndrome and Sjögrens syndrome. Hydroxychloroquine interfers with lysosomal activity and autophagy, interacts with membrane stability and alters signaling pathways and transcriptional activity, which can result in inhibition of cytokine production and modulation of certain co-stimulatory molecules.
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