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Cell Signaling Technology Hydroxychloroquine Sulfate, >98% Purity, 50 mg
SDP

Catalog No. 502050545
Encompass

Hydroxychloroquine Sulfate is a 4-aminoquinoline derivative of quinine that acts as an anti-malaria drug and immunomodulatory agent. It is utilized in studies of rheumatoid arthritis, systemic lupus erythematosus, and various rheumatic diseases due to its ability to inhibit lysosome and autophagosome functions, interfere with cytokine production, and disrupt cGAS/dsDNA complexes to inhibit IFN-β production. The compound also demonstrates antiviral and anti-inflammatory effects, including inhibition of SARS-CoV-2 infection in vitro.

  • Supplied as a lyophilized powder
  • Inhibits IFN-β production with an IC50 of 25 μM
  • Modulates metabolic, cardiovascular, antithrombotic, and antineoplastic pathways
  • For a 10 mM stock, reconstitute 5 mg of powder in 1.15 mL of water

Catalog No. 50-205-0545 Supplier Cell Signaling Technology Supplier No. 85523S
May include imposed supplier surcharges.
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Hydroxychloroquine Sulfate is a 4-aminoquinoline derivative of quinine that acts as an anti-malaria drug and immunomodulatory agent. It is utilized in studies of rheumatoid arthritis, systemic lupus erythematosus, and various rheumatic diseases due to its ability to inhibit lysosome and autophagosome functions, interfere with cytokine production, and disrupt cGAS/dsDNA complexes to inhibit IFN-β production. The compound also demonstrates antiviral and anti-inflammatory effects, including inhibition of SARS-CoV-2 infection in vitro.

  • Supplied as a lyophilized powder
  • Inhibits IFN-β production with an IC50 of 25 μM
  • Modulates metabolic, cardiovascular, antithrombotic, and antineoplastic pathways
  • For a 10 mM stock, reconstitute 5 mg of powder in 1.15 mL of water

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