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Cayman Chemical Hydroxyisovaleric ACD 50g
Supplier: Cayman Chemical 3403050 G
An active metabolite of L-leucine; reduces PIF-induced increases in 20S proteasome activity and NF-κB nuclear accumulation in C2C12 myotubes; inhibits protein degradation and stimulates protein synthesis in the gastrocnemius muscle of cachectic mice bearing MAC16 tumor at 0.25 and 2.5 g/kg; urinary levels are increased in patients with type II diabetes or ketoacidosis
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