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Cayman Chemical Hydroxytyrosol Acetate 50mg
Supplier: Cayman Chemical 4166550 MG
A polyphenol with diverse biological activities; scavenges DPPH radicals in a cell-free assay (IC50 = 1.73 µM); active against V. parahaemolyticus (MIC = 39 UG/ml); inhibits LPS-induced increases in NO, iNOS, and COX-2 levels in isolated mouse peritoneal macrophages at 50 or 100 µM; inhibits hypoxia- and reoxygenation-induced LDH release in isolated rat brain slices; inhibits paw swelling, joint synovial hyperplasia, and cartilage erosion in a mouse model of collagen II-induced rheumatoid arthritis at 0.05% in the diet; decreases serum levels of IgG1, IgG2a, MMP-3, and COMP, as well as levels of TNF-α, IL-1β, IFN-γ, IL-6, IL-17a, and PGE2 in hind paw joint homogenates, in the same model
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