Learn More
STEMCELL Technologies Hygromycin B, Size: 100 mg

Supplier: STEMCELL Technologies 03813
Hygromycin B, an aminoglycoside antibiotic, inhibits the growth of prokaryotic and eukaryotic cells. Specifically, it inhibits protein synthesis by interfering with translocation of the 70S ribosome subunit and inducing misreading of the mRNA template. Hygromycin B has been used to select transfectants in a wide variety of cells including bacteria, protozoans, yeast, fungi, plants, and mammalian cells. Resistance to Hygromycin B is conferred by a gene coding for a phosphotransferase that phosphorylates Hygromycin B, thereby inactivating it. Hygromycin B is an effective agent for the selection and maintenance of bacterial and eukaryotic cells stably transfected with vectors containing E. coli Hygromycin B resistance gene (hyg or hph). This antibiotic is suitable for use in cell culture for the selection of hygromycin-resistant clones when using ClonaCell™-TCS Medium (Catalog #03814), and for the selection of any hygromycin-resistant transfected cell type.
Safety and Handling
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.