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AdipoGen Hypothemycin
Supplier: AdipoGen BVT0067C250
Chemical. CAS 76958-67-3. Formula C19H22O8. MW 378.4. Isolated from Phoma sp. Antifungal. Cytotoxic against some tumor cell lines, partly attributed to inhibition of Ras-inducible genes. Inhibits proliferation of mouse and human T cells. Modulates production of cytokines during T cell activation. Facilitates the ubiquitinylation process of cyclin D1. Potent and selective threonine/tyrosine-specific kinase, MEK and other protein kinases inhibitor in both in vitro and in vivo studies.
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