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Cayman Chemical Hypoxanthine 25g
Supplier: Cayman Chemical 2225425 G
An endogenous purine derivative; intrastriatal administration increases mitochondrial complex II, also known as succinate dehydrogenase, activity and decreases cytochrome c oxidase activity, resulting in neuroenergetic impairment, ATP depletion, and cellular apoptosis in rats at 10 µM; induces hyperuricemia in mice; spinal fluid levels are increased in patients with Lesh-Nyhan syndrome
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