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Medchemexpress LLC HZX-02-059 | 2240205-30-3 | 99.4% | 487.48 | 100 MG
Supplier: Medchemexpress LLC HY112440100MG
HZX-02-059 is a potent methuosis inducer and a dual-target PIKfyve/tubulin inhibitor with anticancer activity. It primarily disrupts the balance of endocytosis and exocytosis, leading to the formation of numerous vesicles and inducing cell death. Additionally, HZX-02-059 promotes cell vacuolization, apoptosis, downregulates the p53 pathway, inhibits PI3K/AKT phosphorylation, and suppresses c-Myc and NF-κB transcription.
- Potent methuosis inducer.
- Dual-target PIKfyve/tubulin inhibitor.
- Exhibits anticancer activity.
- Induces cell vacuolization.
- Promotes apoptosis.
- Downregulates the p53 pathway.
- Inhibits PI3K/AKT phosphorylation.
- Inhibits c-Myc and NF-κB transcription.
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