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Medchemexpress LLC HZX-02-059 | 2240205-30-3 | 99.4% | 487.48 | 25 MG
Supplier: Medchemexpress LLC 25MGHY112440
HZX-02-059 is a potent methuosis inducer and dual-target PIKfyve/tubulin inhibitor with anticancer activity. It primarily disrupts the balance of endocytosis and exocytosis, leading to the formation of numerous vesicles and inducing cell death. This compound also induces cell vacuolization, promotes apoptosis, downregulates the p53 pathway, inhibits PI3K/AKT phosphorylation, and suppresses c-Myc and NF-κB transcription.
- Potent methuosis inducer
- Dual-target PIKfyve/tubulin inhibitor
- Anticancer activity
- Induces cell vacuolization
- Promotes apoptosis
- Downregulates the p53 pathway
- Inhibits PI3K/AKT phosphorylation
- Inhibits c-Myc and NF-κB transcription
- Broad spectrum of cytotoxicity against various human cancer cell lines
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