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Medchemexpress LLC Hzx-02-059 (Compound 13) | 2240205-30-3 | 99.4% | 487.48 g·mol⁻¹ | C27H20F3N5O | 5 MG
SDP

Catalog No. 5000264236
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HZX-02-059 is a small-molecule research compound that induces methuosis and functions as a dual PIKfyve/tubulin inhibitor with reported anticancer activity. It disrupts endocytosis-exocytosis balance to produce extensive intracellular vacuolization and promotes cell death pathways, including apoptosis; reported signaling effects include inhibition of PI3K/AKT phosphorylation and suppression of c-Myc and NF-κB transcription.

  • Induces methuosis and intracellular vacuolization.
  • Dual PIKfyve and tubulin inhibitory activity.
  • Promotes apoptosis and cell death in cellular models.
  • Modulates PI3K/AKT, c-Myc, and NF-κB signaling.
  • Supplied as a high-purity small molecule for cellular assays.
  • Molecular formula C27H20F3N5O; molecular weight 487.48 g·mol⁻¹.

Catalog No. 50-002-64236 Supplier Medchemexpress LLC Supplier No. HY1124405MG
May include imposed supplier surcharges.
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HZX-02-059 is a small-molecule research compound that induces methuosis and functions as a dual PIKfyve/tubulin inhibitor with reported anticancer activity. It disrupts endocytosis-exocytosis balance to produce extensive intracellular vacuolization and promotes cell death pathways, including apoptosis; reported signaling effects include inhibition of PI3K/AKT phosphorylation and suppression of c-Myc and NF-κB transcription.

  • Induces methuosis and intracellular vacuolization.
  • Dual PIKfyve and tubulin inhibitory activity.
  • Promotes apoptosis and cell death in cellular models.
  • Modulates PI3K/AKT, c-Myc, and NF-κB signaling.
  • Supplied as a high-purity small molecule for cellular assays.
  • Molecular formula C27H20F3N5O; molecular weight 487.48 g·mol⁻¹.

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