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Medchemexpress LLC HZX-02-059 (methuosis inducer 1) | 2240205-30-3 | 99.4% | 487.48 | 10 MG
Supplier: Medchemexpress LLC HY11244010MG
HZX-02-059 is a potent methuosis inducer and a dual-target PIKfyve/tubulin inhibitor, demonstrating anticancer activity. This compound primarily disrupts the balance of endocytosis and exocytosis, leading to the formation of numerous vesicles and inducing cell death.
- Induces cell vacuolization and promotes apoptosis
- Downregulates the p53 pathway
- Inhibits PI3K/AKT phosphorylation
- Inhibits c-Myc and NF-κB transcription
- Exhibits broad spectrum cytotoxicity against various human cancer cell lines
- For research use only
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