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Selleck Chemical LLC I-138-E1479-5MG
Supplier: Selleck Chemical LLC E14795MG
I-138 is an orally active potent reversible inhibitor of USP1-UAF1 with IC50 0f 4 1 nM I-138 is structurally related to ML323 and induces the monoubiquitination of FANCD2 and PCNA in MDA-MB-436 cells and increases PCNA and FANCD2 monoubiquitination in HAP-1 USP1 WT cells
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