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Medchemexpress LLC IA9 TFA (human TREM-2 182-190 TFA) | 98.9% | 1001.31 (free acid) | 5 MG
Supplier: Medchemexpress LLC HYP10136A5MG
IA9 TFA is a potent, CNS-penetrant inhibitor of Triggering Receptor Expressed on Myeloid cells 2 (TREM-2). It is capable of reducing proinflammatory cytokines and mitigating joint inflammation and damage in a Collagen-induced arthritis mouse model. This compound is suitable for neuroinflammation PET imaging and research related to rheumatoid arthritis and neuroinflammation.
Features and Benefits
- Potent CNS-penetrant TREM-2 inhibitor.
- Diminishes the release of proinflammatory cytokines.
- Suppresses joint inflammation and damage in experimental arthritis.
- Can be used for neuroinflammation PET imaging.
- Applicable for rheumatoid arthritis and neuroinflammation research.
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