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Abcam IACS-010759, 1MG
Supplier: Abcam AB2869611MG
MW 562.6 Da, Purity >=98%. A potent and selective Oxidative Phosphorylation Inhibitor (IC₅₀ < 10 nM) with potential antineoplastic activity. IACS-010759 robustly inhibits proliferation and induces apoptosis in models of brain cancer and acute myeloid leukemia (AML) reliant on OXPHOS, likely owing to a combination of energy depletion and reduced aspartate production that leads to impaired nucleotide biosynthesis.
The product is subject to the following: Abcam Restricted Use Statement
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