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Medchemexpress LLC Iadademstat (dihydrochloride) | 1431303-72-8 | 99.98% | 1 ML
SDP

Supplier:  Medchemexpress LLC HY12782T10MM/1ML

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Product Overview

Iadademstat (ORY-1001) is a highly potent, orally active, and selective LSD1 (KDM1A) inhibitor that exhibits antileukemic activity. It is intended for research use, particularly in studies concerning relapsed or refractory acute myeloid leukemia.

Features and Benefits

  • Highly potent, orally active, and selective LSD1 (KDM1A) inhibitor.
  • Exhibits antileukemic activity.
  • Can be used for research on relapsed or refractory acute myeloid leukemia.
  • Inhibits the proliferation of cancer cells (H1299 and A549), arrests the cell cycle at G1 phase, and induces apoptosis in vitro.
  • Decreases glycolysis in H1299 and A549 cells by reducing HK2 protein levels in vitro.
  • Demonstrates antitumor activity and increases survival rate in glioblastoma xenograft mouse models in vivo.

Catalog No. 50-003-39983


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